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Sunday night brings one of the biggest spectacles of the NFL season as the Buffalo Bills host the Kansas City Chiefs at Highmark Stadium in what many see as a preview of another deep playoff clash. This isn’t just a meeting between two AFC heavyweights — it’s a battle between two of the sport’s most gifted quarterbacks, Josh Allen and Patrick Mahomes, both capable of redefining what offensive football looks like when the lights are brightest. Read on for the best bet for this event and the analysis in addition to the best betting offers to take full advantage of.
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NFL betting tips: Kansas City Chiefs at Buffalo Bills predictions
Could We Be Set for Another Mahomes–Allen Shootout in Orchard Park?
- Patrick Mahomes has thrown three touchdown passes in three straight games, completing nearly 74% of his throws in that span.
- Buffalo have scored 31 or more points in three of their four home games this season, all of which went over the total line.
- Both teams sit inside the league’s top five for total yards per game, with the Bills leading all teams in rushing yardage.
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Two elite quarterbacks in surging form meet in a venue that regularly delivers points. Mahomes’ recent three-TD streak pairs with Allen’s home efficiency to create a realistic path to six combined passing scores. With both offences top-five for yardage, the 4/1 line captures a matchup primed for fireworks.
The Bills return home in buoyant spirits after hammering Carolina 40–9 last weekend, ending a frustrating run of narrow defeats and spread failures. They finally looked like their old selves, with Allen leading scoring drives at will and running back James Cook bulldozing his way to 216 rushing yards and two touchdowns. Buffalo’s attack found balance again, and that makes them far more dangerous when facing a side as complete as Kansas City. The Bills have won all four of their recent regular-season meetings with the Chiefs, but when it’s mattered most — the playoffs — Andy Reid’s men have had their number.
Kansas City, meanwhile, are building momentum. After a slightly uneven start to the campaign, they have pieced together three straight convincing wins, including a dominant 28–7 victory over Washington last Monday night. Mahomes has been at his majestic best, throwing three touchdowns in each of those games and completing almost 74% of his passes. The return of his top receivers has sharpened the attack, while defensively, the Chiefs have been mean — conceding just 24 points across that winning stretch.
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This game feels like it could explode into another classic. Both sides rank in the NFL’s top five for total yards per game. Buffalo lead the league in rushing yards per outing, while Kansas City continue to stretch defences with their vertical passing. The Bills’ home record on totals is telling — three of their four games at Highmark this year have gone over, with Buffalo posting at least 31 points in each of those outings. Couple that with the Chiefs’ knack for finding rhythm away from Arrowhead, and it’s easy to see why this fixture is expected to light up the scoreboard once again.
Best Bet for the Day: Josh Allen & Patrick Mahomes Over 5 Passing Touchdowns Combined at 4/1
Here at BettingTips4You, we don’t overload our readers with multiple predictions — we deliver one clear, high-quality selection per event. That way, you know exactly where our confidence lies. For this week’s marquee game, our Best Bet is Josh Allen & Patrick Mahomes Over 5 Passing Touchdowns Combined at 4/1 — a value-backed pick in a matchup built for fireworks.
Why back it? Simply put, both offences are trending upward at the same time. Mahomes has thrown three touchdowns in each of his last three games, looking near flawless in execution and decision-making. The Chiefs’ play-calling has rediscovered its balance, allowing Mahomes to exploit one-on-one matchups downfield. Against a Bills defence that has given up at least two passing touchdowns in several of its recent fixtures, his rhythm should continue.
Allen, on the other hand, thrives on these duels. The Buffalo quarterback accounted for four touchdowns in last week’s 40–9 rout — two through the air and two on the ground — but his passing efficiency at home has been particularly impressive. The Bills’ offensive line gives him time to extend plays, and with receivers creating separation in space, expect Allen to test Kansas City deep and often.
Both quarterbacks rank inside the NFL’s top three for total passing yards and red-zone efficiency. Add to that the history between these sides — two meetings last season both cleared 47.5 total points comfortably — and it’s clear the stage is set for a high-scoring thriller. This market combines form, motivation, and offensive chemistry. At 4/1, it’s a bet that captures the essence of what these matchups so often deliver: points, precision, and two generational talents refusing to back down.
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