Guarani vs Universidad de Chile Predictions

Guarani vs Universidad de Chile predictions for this Copa Sudamericana. Guarani host Universidad de Chile on Thursday at Estadio General Pablo Rojas, needing a major turnaround in the Copa Sudamericana knockout second leg after a difficult first-leg result. Read on for all our free predictions and betting tips.

Copa Sudamericana | Jul 24 2025 at 11:00 pm UK at Estadio General Pablo Rojas

Guarani vs Universidad de Chile Predictions

Can Guarani Salvage Pride or Will Universidad Deliver the Final Blow?

• Guarani’s defence continues to crumble – They’ve now let in 12 goals across their last three Sudamericana games, including back-to-back 5-0 defeats.
• Universidad’s away form isn’t bulletproof – The Chileans have only won one of their last six games outside their country, though the quality gap in this tie may cancel that out.
• Guarani struggle to score under pressure – The Paraguayans haven’t scored a single goal in their last three Copa Sudamericana fixtures, raising major doubts over their ability to break through even at home.

Best Bet for Guarani vs Universidad de Chile

On Thursday night, Estadio General Pablo Rojas will witness what is either going to be an extraordinary miracle or a cold, painful confirmation. Guarani host Universidad de Chile in the second leg of their Copa Sudamericana knockout tie, and the size of the mountain they have to climb cannot be overstated. After being absolutely dismantled 5-0 in Santiago, Guarani return to home soil looking for answers, redemption, and—if we’re being completely honest—a small footballing miracle. Universidad de Chile, meanwhile, already have one boot in the last 16 and would need a catastrophic collapse not to stroll through to the next stage.

The Paraguayans have been in freefall, suffering heavy defeats in continental competition, and the 5-0 thumping in leg one followed a near carbon copy scoreline in their previous Sudamericana outing. What’s worse? They haven’t found the back of the net in their last three appearances in the tournament. Their attack looks neutered, their defence disorganised, and their fans frustrated. To make things worse, suspensions and injuries have taken a toll, with Mario Lopez suspended and key absentees like Rolon and Servio still out of the equation.

As for the Chileans, they barely broke a sweat in the first leg. They came, they scored—five times—and left with clean kits and a clean sheet. Alvarez’s side are now unbeaten in five, and although their away form this year has been less convincing, they’ll arrive in Paraguay with confidence surging through the squad.

Best Bet for This Match: Universidad de Chile to Win

After going through every angle and carefully assessing the statistics, here at BettingTips4You we’re confident in highlighting just one single, high-value bet for this clash. We believe that keeping things simple with a Universidad de Chile outright win is the clearest, sharpest angle to take. Unlike tipsters who throw 15 bets at every match and hope one sticks, we focus on quality over quantity, giving you a single prediction per fixture that we believe offers the best return.

Universidad de Chile’s form speaks for itself. Not only did they crush Guarani 5-0 in the first leg, they’ve also dominated at home all season—granted, this match is away, but let’s not pretend Guarani have a fortress to defend. Their home form has been patchy at best, and they’ve now conceded a total of 12 goals in their last three matches in the competition. Meanwhile, La U’s firepower has been relentless, with five different goalscorers in the first leg alone—yes, five. That shows depth, confidence, and tactical clarity.

Sure, you could try to spin a home comeback narrative, but based on all measurable data, you’d be rewriting fiction instead of betting with logic. Even Guarani’s better results at home don’t cover the scale of improvement they’d need. A team that hasn’t scored in three matches and just shipped five goals is hardly the candidate for a turnaround story.

BettingTips4You.com expert quote:

“This is not about hope or fairy tales—it’s about trends, form, and momentum. Universidad de Chile are simply levels above right now, and it would be a surprise if they didn’t complete the job in Paraguay.” – Gerard Gabasa

We’re going for a 2-1 away win here. Guarani might be able to nick a consolation goal at home, but that’s about as generous as it gets. Universidad’s attack should have more than enough in reserve to find the net and cruise through the tie.

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