San Francisco 49ers @ Seattle Seahawks Predictions and Best Bets – NFL tips and preview

Seattle Seahawks host the San Francisco 49ers in Thursday’s NFL action. Week 6 of the 2024 NFL season begins with two teams that are coming from disappointing losses, set to face each other on Thursday Night Football. Click here for the latest tips, analysis, and best bets for this matchup.

SEA Seahawks

NFL | Oct 11th, 2024 at 1:15am UK at Lumen Field

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San Francisco 49ers @ Seattle Seahawks Predictions

Can the Seahawks Stop the 49ers’ Slide in a Must-Win Clash?
  • The 49ers have only managed to score 22 points in the final quarter across five games this season, averaging just 4.4 points.
  • Seattle have lost two consecutive games, but they are 3-2 overall, still leading the NFC West.
  • San Francisco’s defence ranks 22nd in opponent third-down conversion rate, allowing teams to convert 43.33% of the time.

Our Tips

Kansas City Chiefs +2
10/11 - odds when tipped
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Reasoning
Backing the Kansas City Chiefs +2 seems a smart bet, given their knack for winning despite challenges, strong defensive play, and Andy Reid’s post-bye tactical advantage. While San Francisco has talent, Kansas City's consistency and creativity give them the edge.
Total Points Under 47
10/11 - odds when tipped
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Reasoning
Backing under 47 points seems wise, as both teams boast strong run defences, limiting ground play. Offensive inconsistencies, key injuries, and turnover issues suggest a more defensive game, likely falling short of the points total.

The tension is palpable as the San Francisco 49ers face off against the Seattle Seahawks in a crucial Week 6 Thursday Night Football clash. Both sides are coming off disappointing losses, and the stakes couldn’t be higher in this NFC West rivalry. The 49ers, who once led the NFC with confidence, find themselves reeling at 2-3, while the Seahawks are holding on to a 3-2 record, still leading the division but far from comfortable. Both teams need a win to regain momentum, and that’s what makes this matchup so tantalising.

Best Bet: Seahawks +3.5

Now, the first prediction that looks extremely enticing for bettors is backing the Seattle Seahawks at +3.5. Why? Well, let’s dive into it. While the 49ers are traditionally a strong outfit, their form this season has been inconsistent. They’ve shown a concerning inability to close out games, especially highlighted in their recent meltdown against the Arizona Cardinals. Despite leading comfortably at halftime, San Francisco’s defence collapsed in the second half, and this isn’t an isolated incident. It’s a trend, and worrying for any team hoping to compete at the highest level.

Seattle, on the other hand, have their own problems. They’ve lost two games on the bounce, and their defence was shockingly porous last week against the New York Giants. But—and this is important—there’s more resilience in this Seahawks side than people give them credit for. The Pacific Northwest is never an easy place for visiting teams, and the Seahawks will relish playing this one in front of their home fans, who will undoubtedly bring the noise.

The Seahawks also have Geno Smith leading the charge, and while he didn’t have his best game last week, he’s shown he can bounce back. The supporting cast around him is talented, and San Francisco’s defence, which has struggled with injuries and poor form, isn’t the brick wall it once was. The 49ers’ secondary, in particular, looks vulnerable, and with Seattle’s offence showing flashes of brilliance earlier in the season, expect them to keep this game within a field goal. Seattle might not necessarily win, but they should certainly be able to cover the +3.5 spread.

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Prediction: Totals Under 48.5

The second prediction to consider here is the totals under 48.5. This might come as a surprise, given both teams’ offensive potential, but the reasoning is sound. Firstly, the Seahawks’ defence, despite its struggles last week, should tighten up at home. They were embarrassed by the Giants and will be desperate to avoid a similar showing. While they might not completely shut down San Francisco, they will aim to control the tempo and keep things tight, especially with key players returning to the fold.

San Francisco, meanwhile, have been erratic when it comes to putting up points. Without Christian McCaffrey, they’ve found it difficult to sustain drives, and their inability to close out games has cost them dearly. Yes, they’ve got offensive firepower, but their efficiency, particularly in the fourth quarter, has been abysmal. They’ve averaged just 4.4 points per game in the final 15 minutes this season, which speaks volumes about their late-game struggles.

Both teams are also coming off bruising losses, and we often see defences tighten up in these situations. Desperation breeds caution, and it’s likely both sides will be wary of making the mistakes that cost them dearly in Week 5. Expect a gritty, defensive battle rather than a shootout, making the under 48.5 the sensible play here.

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Graham Hartshorn
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