San Francisco 49ers @ Los Angeles Rams predictions for this NFL showdown. This is an ideal opportunity for the 49ers to recover after their week two setback, as they aim to regain momentum against a potentially less challenging opponent. Read on for all our free predictions and betting tips.
NFL | Sep 22, 2024 at 9:25pm UK at SoFi Stadium
 | NFL LIVE |
San Francisco 49ers @ Los Angeles Rams Predictions
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Can the Depleted Rams Withstand the 49ers’ Onslaught?
- Matthew Stafford has been sacked seven times over two games, averaging 3.5 sacks per game.
- The 49ers have recorded five sacks this season against stronger offensive lines.
- The Rams’ leading trio of receivers have a combined total of 17 catches, fewer than Cooper Kupp’s individual 18.
Our Tips
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Reasoning | |
As the San Francisco 49ers prepare to face the Los Angeles Rams this Sunday, both teams are dealing with significant injury concerns that could heavily influence the outcome. The 49ers are looking to bounce back after a disappointing performance in week two, while the Rams are grappling with a depleted offensive line and missing key offensive weapons. With both sides eager to secure a win despite their setbacks, this matchup promises to be a test of depth and resilience.
Best Bet: San Francisco 49ers to record at least three sacks against the Los Angeles Rams
Matthew Stafford is set for a challenging evening as he faces a relentless San Francisco defensive unit. In the Rams’ recent encounter with the Cardinals, Stafford was sacked five times, highlighting vulnerabilities in his protection. The situation appears even more dire this week, with Los Angeles confirming the absence of four offensive linemen, and right guard Kevin Dotson having spent time on the injury report. This depleted line is unlikely to offer Stafford the time he needs in the pocket, leaving him exposed to the 49ers’ pass rush.
The 49ers have already recorded five sacks this season against teams with more robust offensive lines, such as the New York Jets and Minnesota. Although there was concern earlier in the week about Nick Bosa’s availability, indications suggest he will play, bolstering an already formidable defensive front. Even without Bosa, San Francisco boasts significant talent in players like Kevin Givens, Fred Warner, and Leonard Floyd, all of whom have registered sacks this year.
The Rams’ receiving corps is also weakened, with both Cooper Kupp and Puka Nacua sidelined. This leaves Demarcus Robinson, Tyler Johnson, and Tutu Atwell, who have combined for just 17 catches so far—less than Kupp’s individual total of 18. With limited options downfield and a patched-up offensive line, Stafford is likely to hold onto the ball longer, increasing the chances of being sacked.
Considering that the Rams have allowed an average of 3.5 sacks per game and the 49ers are facing a battered offensive line, betting on San Francisco to achieve at least three sacks seems a prudent choice.
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Second Prediction: San Francisco 49ers to cover the spread against the Los Angeles Rams
The 49ers are poised for a strong performance after an underwhelming showing in their previous game. Historically, San Francisco’s coach Kyle Shanahan has had the upper hand in matchups against Rams’ coach Sean McVay, which adds a strategic advantage. Despite the initial line favouring the 49ers by fewer than seven points, the recent injury news tilts the scales further in San Francisco’s favour.
The Rams are not only missing key offensive players but are also struggling defensively, with three starting defensive backs out of action. This defensive frailty was evident in their heavy defeat to the Cardinals, and facing a 49ers offense that surprisingly leads the league in passing yards through two weeks only compounds their problems.
On the offensive side, San Francisco’s line has held up well, giving their quarterback ample time to exploit opposing defences. With the Rams’ defence ranking in the bottom five for adjusted line yards, the 49ers’ offence should find plenty of opportunities to score. Given these factors, backing San Francisco to cover the spread appears to be a sound wager.
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