NFL betting tips: Miami Dolphins @ Buffalo Bills predictions, preview and best bets

Thursday night’s NFL action brings a solitary but potentially explosive clash to the table as Week 3 of the 2025 season kicks off in style. With only one fixture scheduled, all attention turns to Highmark Stadium, where the Buffalo Bills will welcome their divisional rivals, the Miami Dolphins, in a primetime AFC East encounter. Set to begin at 1:15am UK time in the early hours of Friday morning, this contest will be broadcast live on Sky Sports NFL and Sky Sports Main Event – the perfect late-night feast for gridiron enthusiasts. Read on to find a detailed preview and the best bet recommendation for this clash, and don’t forget to take advantage of the selected betting offers listed below to maximise your betting value.

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NFL betting tips: Miami Dolphins @ Buffalo Bills predictions

Is Defence Optional in This AFC East Showdown?
  • Buffalo have averaged 35.5 points per game across their opening two fixtures.
  • Miami’s defence has allowed 33 points in each of their first two outings.
  • Tyreek Hill, Jaylen Waddle, and De’Von Achane combined for 269 receiving yards in Week 2.

Our Best Bet

Each Team Over 2 Touchdowns
5/2 - odds when tipped
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Reasoning
Buffalo are averaging over 35 points per game, while Miami showed attacking promise with 27 points last week despite defeat. With the Dolphins’ defence leaking 33 points per game, this matchup looks primed for touchdowns on both sides. Backing each team to score over two TDs offers excellent value at 5/2.

The atmosphere is poised to be electric, with Buffalo hoping to keep their momentum alive following an unbeaten start to the campaign. After convincing victories over two strong AFC contenders, the Bills arrive at this one as heavy favourites. In contrast, Miami’s start has been anything but smooth. Two losses from two, including a bruising defeat to Indianapolis and a narrow reverse at home to New England, have left the Dolphins with much to prove on both sides of the ball.

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Despite their poor record, Miami still possess weapons that could turn this into a shootout – particularly when factoring in Buffalo’s offensive dominance thus far. With the Dolphins’ defence showing serious vulnerabilities and the Bills’ attack firing on all cylinders, this meeting has the potential to become an early-season classic filled with points, plays, and pressure.


Best Bet for Dolphins at Bills: Each Team Over 2 Touchdowns at 5/2

At BettingTips4You, our philosophy is built around delivering one high-quality recommendation per event rather than overwhelming readers with multiple options. This approach promotes clarity, focus, and ultimately more accountable betting – our readers always know precisely where our conviction lies. For tonight’s marquee NFL fixture, we’re siding with Each Team Over 2 Touchdowns at 5/2 as our Best Bet of the Day.

There are compelling reasons to expect both teams to find the end zone multiple times, even though Miami enter this clash as double-digit underdogs. Buffalo’s offence, orchestrated by the reigning league MVP, has already racked up over 900 yards in just two games and is averaging a potent 35.5 points per outing. Their offensive line has been imperious, allowing just two sacks across eight quarters, while running back James Cook has emerged as a focal point with 5.2 yards per carry and three touchdowns already.

Yet it’s not just Buffalo who can contribute to the scoring tally. Miami’s attack showed significant improvement in Week 2, with Tua Tagovailoa completing 81% of his throws at nearly 10 yards per attempt. Wideouts Tyreek Hill and Jaylen Waddle combined for 177 yards last week, and De’Von Achane was electric in the passing game with 92 receiving yards. Although they fell short again, the Dolphins still put up 27 points against the Patriots.

The primary concern for Miami remains their defence, which has conceded 33 points in both of their matches so far. Their inability to prevent drives – evidenced by New England converting 7 of 12 third-down attempts and three of four red zone trips – means they’re likely to be chasing the game and responding with aggressive offensive play-calling. This game script bodes well for touchdowns on both sides, particularly given the dry, warm weather expected at Orchard Park.

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Steve Harrington
Steve Harrington is a sportswriter whose heart beats for football. With a passion that began in the grassroots, he's witnessed the magic of the game from local pitches to grand stadiums. Over the past 7 years, Steve has lent his expertise to several online publications, chronicling the ever-evolving world of football. Beyond his professional pursuits, he holds a special affection for Burnley Football Club, cherishing every triumph and tribulation. Steve believes in the power of storytelling and its ability to bring the beautiful game closer to its ardent fans.