NFL betting tips: Jacksonville Jaguars vs Kansas City Chiefs predictions, preview and best bets

The final act of the NFL weekend unfolds under the bright Florida lights as the Jacksonville Jaguars welcome the Kansas City Chiefs to EverBank Stadium on Monday night. Kicking off at 1:15am UK time (Tuesday morning) and shown live on Sky Sports NFL and Sky Sports Main Event, this Week Five clash promises to close the round with intensity and high-calibre football. Read on for the best bet of the night and the analysis in addition to the best betting offers to take full advantage of.

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NFL betting tips: Jacksonville Jaguars vs Kansas City Chiefs predictions

Can Jacksonville’s Grit Halt Kansas City’s Championship Rhythm?
  • Jacksonville have ranked inside the NFL’s top five defences after four games this season.
  • Kansas City scored four passing touchdowns in their latest victory over Baltimore.
  • Travis Etienne Jr. leads a Jaguars unit placed in the league’s top ten for rushing yards.
Best Prediction
NFL • Oct 6, 2025
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🎯 FREE Travis Etienne Jr. To Score First Touchdown
Odds 6/1

Travis Etienne Jr. has been the spark in Jacksonville’s ground game, consistently driving early momentum. With the Jaguars focusing on establishing control through rushing plays, his agility and power make him an ideal candidate to find the end zone first. At 6/1, this represents strong value for Monday’s opener.

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Jacksonville enter this encounter with confidence after a strong start to their campaign, boasting a 3–1 record under new head coach Liam Coen. Their impressive defensive structure and revitalised running game have been at the heart of their early success, including a resilient 26–21 triumph on the road against the 49ers. Ranked among the league’s top five defences and top ten rushing units, the Jaguars have showcased organisation and energy in equal measure.

Travis Etienne Jr. has spearheaded their ground attack, providing balance and rhythm to an offence that still seeks sharper execution in the passing game. Quarterback Trevor Lawrence, however, continues to wrestle with inconsistency, occasionally undermining his side’s strong field position with unforced errors.

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Meanwhile, the Kansas City Chiefs arrive with a 2–2 record and a growing sense that their early struggles may already be behind them. Their home dismantling of the Baltimore Ravens in Week Four served as a clear statement of intent. With wide receiver Xavier Worthy back from injury, Kansas City’s offensive structure looked more dynamic, enabling Patrick Mahomes to produce a four-touchdown performance that reminded the league of his unmatched creativity. The defending AFC champions appeared to rediscover their trademark composure and efficiency, dominating possession and dictating tempo. Despite their relatively modest record, the Chiefs remain a formidable opponent—one whose offensive ceiling few teams can match when rhythm takes hold.

With both teams coming off significant victories, this encounter carries the feel of an early-season litmus test. Can Jacksonville’s defensive resilience and Etienne’s ground control unsettle a Chiefs side that seems to have rediscovered their swagger? Or will Kansas City’s offensive versatility and championship pedigree prove too strong for a side still finding its full identity? The stage is set for a compelling Monday night encounter that should keep fans glued to their screens until the final whistle.

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Best Bet for Today’s Action: Travis Etienne Jr. – First Touchdown Scorer

At BettingTips4You, we stand by a clear and disciplined approach: one game, one prediction. By offering a single expert selection per event, we prioritise quality over quantity—making it simpler for our readers to follow, evaluate, and trust each recommendation. Our focus this time is on Travis Etienne Jr. to score the first touchdown of the game, a choice grounded in recent form and tactical logic.

Etienne has become the heartbeat of Jacksonville’s offence, consistently providing the explosive runs that ignite early drives. With the Jaguars ranking among the NFL’s top ten in rushing yards, their opening sequences have leaned heavily on the ground game. The balance that Etienne offers—blending agility, acceleration, and decisive vision—has been central to their success, particularly in red-zone situations where his low centre of gravity makes him difficult to stop.

Kansas City’s defence, while improved, can be vulnerable to early momentum shifts on the ground, particularly before adjustments settle their formation. Given Jacksonville’s inclination to establish tempo through their running plays, Etienne is perfectly positioned to capitalise on initial possession opportunities. Whether from an orchestrated red-zone sequence or a broken play exploiting space, his explosiveness gives him the edge to open the scoring. With confidence high and the offensive plan geared around his influence, Etienne represents both value and logic as the first touchdown scorer tonight.


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