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Two of Brazil’s most historic clubs meet at the Arena do Gremio on Thursday night, as Gremio host Sao Paulo in a crucial Serie A clash with Copa Sudamericana implications. The hosts are desperate to climb into the top 12, while the visitors are targeting a push towards the Copa Libertadores qualification zone.
This fixture promises attacking flair and moments of individual brilliance, and our carefully constructed Bet Builder highlights key angles based on player influence, tactical setups, and form trends. Each selection has been chosen to balance value and realism, reflecting both sides’ current strengths and weaknesses.
Here’s our Bet Builder pick for Gremio vs Sao Paulo, which has been placed with Bet365!
Why this pick
Gremio’s home matches tend to open up, and defensive absences raise exposure. Sao Paulo push full-backs high and sustain pressure. With both sides carrying reliable attacking pieces, a goal each matches the recent form and tactical setup.
Why this pick
Operating as a second striker/creator, Luciano finds pockets between the lines and works the keeper from varied angles. With Gremio short at the back, Sao Paulo’s rotation up front should free him for multiple accurate efforts.
Why this pick
Henrique has become Gremio’s primary outlet, attacking low crosses and rebounds. Sao Paulo can be vulnerable to transitions behind advanced wing-backs; expect the centre-forward to generate at least two on-target looks.
BTTS suits the game state, while Luciano’s shot volume and Henrique’s penalty-area presence provide dependable player angles. The legs complement each other for a value 20/1 combination in Porto Alegre.

Gremio vs Sao Paulo Bet Builder Tip
Both Teams to Score
Goals appear a realistic prospect at both ends. Gremio have demonstrated resilience at home, winning five of their eight league victories in Porto Alegre, yet their defensive line has shown signs of vulnerability in recent outings. The absence of key defensive figures such as Walter Kannemann through suspension, alongside multiple injuries, leaves Mano Menezes with limited options at the back.
Sao Paulo, under Hernan Crespo, adopt a proactive attacking structure that favours overlapping full-backs and forward runs from midfield. Even without their leading scorer Andre Silva, Crespo’s side have maintained a habit of creating opportunities, averaging over a goal per game across their last five away fixtures.
For Gremio, Andre Henrique’s inclusion in the starting eleven has injected renewed energy in attack. The forward has displayed strong link-up play with Cristian Pavon and Tomas Aravena, ensuring the hosts remain a consistent offensive threat.
Given both teams’ respective form — Gremio’s preference for open games at home and Sao Paulo’s willingness to take risks — a scenario where both find the net seems a solid expectation. Historically, this fixture has also produced competitive scorelines, adding further weight to the prediction.

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Luciano Neves – 2+ Shots on Target
Luciano Neves has long been Sao Paulo’s creative heartbeat, operating as both a secondary striker and an advanced playmaker. Despite their mixed recent form, Luciano continues to produce high shot volumes, often testing goalkeepers from inside and outside the box. His confidence and versatility make him a key component in Crespo’s tactical approach.
With Gremio missing several first-choice defenders, including captain Kannemann and full-back Leonardo, Luciano will likely find more space to exploit. Sao Paulo’s system encourages fluid movement across the front line, and Luciano’s ability to drift into pockets between midfield and defence could create multiple shooting opportunities.
Statistically, he averages close to two efforts on target per match when facing mid-table sides, making this bet both data-driven and situationally strong. Moreover, Gremio’s temporary goalkeeper Gabriel Grando has faced one of the league’s highest shot counts since replacing Tiago Volpi, suggesting that Luciano may again feature heavily in Sao Paulo’s attacking statistics.
Andre Henrique Martins – 2+ Shots on Target
With Martin Braithwaite sidelined after surgery, Andre Henrique has become Gremio’s primary attacking outlet. The young forward has responded impressively, scoring in recent home performances and maintaining a consistent threat inside the penalty area. His direct style and ability to take on defenders one-on-one have made him a focal point in Menezes’ adjusted front line.
Against Sao Paulo, Henrique’s role becomes even more vital. The visitors, though strong in attack, have occasionally looked unsettled when defending transitions, especially with their wing-backs pushed high. This leaves gaps that Gremio’s wingers and central forward can exploit. Henrique, often positioned to receive low crosses and rebounds, is likely to register multiple attempts on goal.
Gremio’s approach under Menezes prioritises high-tempo pressing and quick counterattacks, creating frequent shot opportunities even when possession statistics are modest. With Henrique’s improving confidence and positioning instincts, backing him for two or more shots on target aligns with both current form and tactical patterns.
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