NFL betting tips: Atlanta Falcons at Arizona Cardinals predictions, preview and best bets

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Can the Falcons Finish Strong and Exploit Arizona’s Defensive Woes?

The NFL regular season is winding down, and Week 16 brings us a matchup between two franchises looking to end disappointing campaigns on a high note. Read on for our best betting tips for this match.

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NFL betting tips: Atlanta Falcons at Arizona Cardinals predictions

  • Bijan Robinson’s Dominance: The Falcons running back has accumulated 1,174 rushing yards this season, averaging 5.0 yards per carry.
  • McBride’s Historic Pace: Arizona tight end Trey McBride has recorded 1,071 receiving yards in just 14 games.
  • Defensive Collapse: The Cardinals have allowed 40 or more points in four of their last six games.

Falcons vs Cardinals — bet365 Market Snapshot

Swipe through key markets with illustrative probabilities and live bet365 odds for Week 16.

Atlanta Falcons
Falcons
vs
Arizona Cardinals
Cardinals
Main Market • Moneyline
Winner Prediction

Atlanta enters as the clear favorite, with momentum on their side against a Cardinals team on a six-game skid.

Falcons
62%
bet365 8/13
Cardinals
38%
bet365 11/8
Totals • Points
Scoring Expectations

Markets lean towards a high-scoring game given Arizona’s defensive struggles and Atlanta’s recent offensive output.

Over 48.5
Under 48.5
Player Props
Key Offensive Weapons

Bijan Robinson is the engine of the Falcons’ offense, while Trey McBride offers the most consistent threat for Arizona.

Bijan 100+ Rush
45% bet365 6/5
McBride 60+ Rec
69% bet365 4/9
Swipe left or right to browse markets. Odds are subject to change and may differ from live bet365 prices.

The 5-9 Atlanta Falcons travel west to face the 3-11 Arizona Cardinals in a Sunday afternoon contest that, on paper, appears to lack playoff stakes but certainly not intrigue. For Atlanta, there is a sense of momentum following a dramatic victory over the Tampa Bay Buccaneers, where they erased a two-touchdown fourth-quarter deficit to win on Thursday Night Football.

Offensive Engines: Robinson vs McBride

While wins have been scarce, both teams feature dynamic playmakers who are delivering elite production this season.

Bijan Robinson
Run Game Elite
1,174
Total rushing yards (5.0 avg)

Robinson is the heartbeat of the Falcons’ offence, consistently churning out yardage and moving the chains.

Trey McBride
Historic Pace
1,071
Total receiving yards

The Arizona tight end is having a career year, serving as the primary target in the Cardinals’ passing attack.

Defensive Collapse: Arizona’s Struggles

The Cardinals’ recent form has been defined by an inability to stop opponents from scoring heavily.

Cardinals Defence
Leaking Points
40+
Points allowed in 4 of last 6 games

Conceding 45 and 40 points in consecutive weeks highlights the immense opportunity for the Falcons’ offence.

Cardinals Form
11 Losses
1-11
Record in last 12 games

A drastic slide in form sees them entering this contest with virtually no momentum.

That mini-bye week has afforded Raheem Morris’ squad extra rest and preparation time, a luxury not afforded to their hosts.

Arizona, meanwhile, finds itself in a tailspin. Having lost 11 of their last 12 games, the Cardinals are struggling to find answers on both sides of the ball. Their current six-game losing streak has been defined by defensive capitulation, a trend that Atlanta will be desperate to exploit.

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While the quarterback matchup features two veterans in Kirk Cousins and Jacoby Brissett—described by many as solid if not overly dynamic at this stage of their careers—the potential for scoring remains high given the specific vulnerabilities on display. With the Falcons looking to build on their recent offensive explosion and Arizona playing for pride in front of their home fans, this game could open up significantly more than the standings suggest.

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Best Bet

At BettingTips4you.com we publish ONE primary pick per event to keep things clear and accountable.

Rico Dowdle 100+ Rushing Yards at 13/2

The modern NFL dictates that when two teams with nothing to lose meet late in the season, defensive intensity can often wane, leading to higher-scoring affairs. The evidence for Atlanta holding up their end of the bargain is substantial. Coming off a game where they scored heavily to upset a division rival, their confidence is high. The Cardinals’ defence has essentially “dropped off a cliff,” conceding points at a rate that makes three touchdowns for the opposition feel like a baseline expectation rather than a ceiling. When you consider that Atlanta has playmakers like Robinson and Pitts operating against a unit allowing 40+ points regularly, the Falcons’ offensive production seems the safer part of this equation.

However, for this bet to land, Arizona must also contribute. Despite their 3-11 record, the presence of Trey McBride is a massive factor. He torched Houston’s top-ranked defence recently, proving that matchup difficulty is rarely an issue for him. Atlanta has defended tight ends well statistically, allowing a low percentage of targets to the position, but McBride is the focal point of this offence, not just a cog. If Atlanta takes a commanding lead early—as the spread suggests they might—Arizona will be forced to abandon the run and throw the ball. This volume passing game, led by Brissett, naturally leads to scoring opportunities, even if they come late in the fourth quarter.

What could go wrong The primary risk lies with the quarterbacks. Both Cousins and Brissett are veterans who manage games rather than explode them. If Atlanta establishes a lead and decides to lean heavily on the run game to drain the clock without pushing for extra scores, the game could stagnate. Additionally, injuries are a concern; while London is expected back, any setbacks to him or Pitts could limit Atlanta’s red-zone efficiency. Finally, if the Falcons’ pass rush continues its overachieving form and sacks Brissett frequently, it could kill Arizona’s drives before they reach the end zone.


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